It depends on the burner and media you use. But its always safer to burn at lower speed (2x or 2.4x).
btw, I tried HoD 2/3 (decrypted) on the loader 0.3 beta. Unfortunately 2 still doesn't load properly, which is the same with waninkoko 0.1 loader.
I'd suggest you burn the game again with lower speed, or change the media. I also had the same problem with Mario Kart burnt with 4x. But when it is burnt with 2x everything works well.