It may cause issues and that's highly dependent on how the CHD was made since there's different levels of compression
That's just not possible, you might have changed from dynarec to lightrec without realizing it, CHD has no bearing on how fast...
The big ones are still the same, Tekken3 De-interleaced, Bloody Roar at 480i, the Square RPGs, the obscure demo samplers and Silent Hill and Tomb Raider with proper dither.
Thanks for the new build.
Magic Knight Rayearth (4M) (Japan) : GAME BOOTS AGAIN! FULL SPEED SEEMINGLY!, however VDP1 clipping/masking/background transparency still doesn't work, which gets in the way of some parts that might difficult playing...
Added a couple more tested games in anticipation for the next build and upcoming re-tests.
Check the posted video for some of the new titles that are booting and playing again.