Thus far none, though quite some have come close.
Most recently is Florence, a...I supose you could call it a narration game, but the story's told without words and is stringed together by minigames. In nature, the game is rather barebones (girl falls in love with guy, they move in, grow apart, separate), but the HOW is incredible in its simplicity.
For example: when guy moves in, he has some stuff. But...Florence (our protagonist) doesn't have enough room to store everything. So it's up to you (the player) to decide what stuff Florence has stays, what gets replaced by guy's stuff and what gets tossed out. It's a minigame without really a winning or a losing outcome (you don't "lose" in this game), but because you don't know in advance whether that matters and because you're already emotionally invested, these choices still matter.
One I'd absolutely recommend to those having a naive image of a relationship, by the way. Too bad it's waaaay to short (heck...It'd be too short if it was twice the length).