If you want to use Yuzu, you will have to download the latest version of
Yuzu EA. Then, you will want to download this
patch and add it to TotK as a mod. You should now be able to play on Yuzu without any problems. Additionally, you may add this
resolution fix to the main.pchtxt of the mod to remove the game's ugly downscaling and aliasing. The resolution fix works on Ryujinx as well. The resolution fix may worsen your performance depending on your PC specs and what API you use, in my case it didn't hurt my performance that much