Jeez, this game's difficulty curve is fairly ok, until you get to the first dark tumors, then it's like hitting a brick wall.
These things have beat me back harder than the final boss of the last game. Although I'm playing on hard mode, I still managed to get As and S ranks until reaching that mission, where I have been unable to beat it after 7 attempts. Taking a bit of a break. =_=
Healing Touch ability has been nerfed a bit. Tools are breaking down quicker, as well.
The voice dubs aren't that bad, though.
New art style is interesting.
Overall, this game is MUCH tougher than the last one. The control scheme has also been worked on a bit, to give tools easier access. This game is not meant for people who did not play the first one, as it pretty much picks up right where the last game left off, 3 years later.
It's tough, but I LOVE it. Something to give me a challenge with. =3