It's not. Who am I to judge. I am assuming if you are willing to do mod this is because you already own it.
A Raspberry Pi 5 might be twice as powerful at half the budget otherwise.
GB carts solved this by writing to arbitrary ROM addresses to inform the mapper to switch to specific banks. The trick is understanding the ROM mapper is physically inside the cart.
Of course it would need to be a custom mapper. Emulators will...
From a technical standpoint should run, at least, all portable platforms predating the PSP. Special mention to the DS as the screen has touch controls. I would expect PS1 and below but let me hold for N64 or Sega Saturn. DOS games, such as DOOM...