I don't think so. Most networking options in emulators are quite limited when it comes to speaking to real DS hardware.
You can run the download station rips on a DS flash cart on a DS and have those send things out but the DS wifi hardware is quite custom so not all that much was done outside of things like wifime. The Wii homebrew presumably having the necessary bits to speak to the DS.
There is also stuff like
https://gbatemp.net/threads/haxxstation-ds-download-station-exploit.473648/
If you have DS homebrew already running then it can speak to normal networks and get things that way.
If you mean you have stuff like the download station rips and want to play the individual games contained within then most times download play ROMS (usually seen at utility.bin, probably in a folder called dwc, and files with the extension srl inside ROMs) are just DS ROMs and you can extract those with things like tinke, ndstool/dslazy/dsbuff, crystaltile2, ndsts... (there are hundreds of programs that can read the DS file system and extract files) and run them directly in emulators.