The Wii is more safe than vWii, faster to boot into.
The wii has few protection against semi-brick or even full brick (based on your console's date) and more tools you can use.
vWii doesn't have any brick prevention, and you can't fix a full brick. A lot of homebrew system tools from Wii shouldn't be used on vWii.
If you plan only to launch homebrew/emulators/loaders, they are both fine.
like I said, wii is faster to boot and can autoboot into homebrew.