Hacking which cIOS works best with which usb loaders

[AtMyWiitsEnd]

trawling through the forums found many psuedo answers but nothing concrete or when i did they were talking about old things which i cant find any morei have usb loader gx wananikos 1.5 and coverfloader but none copy and play resident evil 4 they all copy but none play also i am running cIOS249 rev 14