Flatmod for disc back-ups (Gamecube mostly, but some wii games that I've been too lazy to migrate to WBFS).
Configurable USB loader 50c w/WD MYBook 1TB (300 GB dedicated to WBFS).
Much prefer the softmod w/USB loading. Faster load times+++ Would have done it sooner, but I have a LU65+ Wii (bought in Feb 2009) and chose the flatmod route in April because I'm a bit impatient that way (no soft-mod worked for my Wii for a good while)... Anyhoo... Also using cios 249/250 rev14 and not a single problem to report (Rock Band, GH, Band Hero, Metroid Trilogy, New SMB, SSMB (DVD5, of course), incl.). Couldn't be happier (and my kids think I am a god amongst men - particularly my 4 yr. old boy who just today yanked a "toad" stuffed toy from under his shirt and whacked me in the face with it prior to giggling - I suppose I had that coming)! Bad Daddy!
P.S. Thankful for (but haven't had to REALLY use - yet, despite soft modding three Wiis [2 in the past week] now...) PreLoader / Bootmii - the two combined made my plunge into darkness that much easier (or at least, tolerable [per wifey])!