Another unpopular opinion: within the Ratchet & Clank series, my favourite female character is, by far, Angela Cross from 2/Going Commando.
Sure, I know exactly what others would say to disparage this choice compared to later characters like Talwyn or Rivet - "Angela is only depicted as competent before her gender is revealed; once it is, she becomes a klutz and is captured by Thugs-4-Less".
That might be true, but it doesn't make her any less important.
At the start of R&C: GC, her identity is hidden as she steals "the experiment" (later renamed to the Protopet) and it's up to Ratchet to retrieve it. Angela manages to abduct Clank from his apartment on Endako, requiring Ratchet to rescue him, and she's able to evade the eponymous duo until Siberius, where Ratchet defeats her and rescues the Protopet.
After that, R&C meet with the supposed president of Megacorp, Fizzwidget, who takes the Protopet and "accidentally" dumps them on Tabora; after the duo escape the underground caverns, Angela returns, demanding the return of the Protopet and then finally starting to explain how dangerous the blue fuzzball actually is.
In order to infiltrate Megacorp HQ and terminate the Protopet menace, the duo requires Angela's old Megacorp employee ID, as she used to be a skilled scientist there until the Protopet incident; indeed, it's her Helix-o-morph invention that finally ends the crisis, with her using it on the giant mutated beast.
I find Angela more likeable than later R&C gals like Sasha, Talwyn, and Rivet, as she's not an explicit leader (unlike Sasha) or fighter (Talwyn and Rivet); most of her scenes are humorous in one way or another, both as the anonymous thief and after she's unmasked, and it's never in an over-the-top way either. She genuinely wants to keep the Bogon Galaxy safe, hence her actions in initially stealing the threat and working with R&C to eliminate it afterwards, but as she's more of a scientist than a fighter, she can't do it herself.
Angela Cross is just inherently more likeable than Talwyn and Rivet, in my eyes.