Basically, the current exploits we have now that allow us to run Loadiine and other homebrew are temporary kernal exploits. This means we get limited access to some of the WiiU's resources. They have to be activated every time the console is powered on, and the hacks are essentially deleted when the console turns off. As such, none of the current "hacks" we have now are permanent; none of them save to the memory, and there are zero chances of bricking your console.
Essentially what IOSU will do is give hackers all or nearly all access to all of the WiiU's resources. This leads people to believe that once this unicorn of an exploit is released, we'll be able to hack the U as the Wii was hacked, but that's mere speculation. On it's own, IOSU will do nothing.
But once it's released there will be more possibilities for more homebrew and other tools that we can use.
I'm personally hoping for NAND access, Loadiine USB compatibility and online functionality, all things that we believe may be possible.
That's if it's ever released.