I haven't tried that game, but these guidelines work well for me.
Always enable 'force r/w' if the box for it shows up, regardless of the read method. Many games don't need it, but some do and I have yet to find any reason not to enable it.
Only enable soft reset if you actually want to use it. It breaks a small pecentage of games, and if you don't use it it just adds trouble with no benefit.
Here's what I do:
1) Dofat, force r/w, trim.
2) Safe mode, force r/w, trim.
I don't think I've tried any games that worked at all that didn't work with one of those settings. I've never found a game that didn't work with trimming, but I don't play mutiplayer.
Here's what I would do if I cared about soft reset:
1) Dofat, soft reset, force r/w, trim.
2) Normal, soft reset, force r/w, trim.
3) Dofat, force r/w, trim.
4) Safe mode, force r/w, trim.
BTW, several people have gotten the U-disk manager running on macs:
http://gbatemp.net/index.php?showtopic=38737
http://gbatemp.net/index.php?showtopic=38616