I don't see why'd you'd want to do this. You will need a Wii capable of reading DVD discs(older version) which I would guess you have if you're asking this. If WiiSX supports loading from DVD(which I believe it's supposed to) then it should be as simple as dropping the ISO or CUE and BIN files(if WiiSX accepts that format) onto a blank DVD and burn the disc. WiiSX should give you the option of loading from a DVD, then you should be able to select the game you want from the menu. I would honestly suggest going USB Hard Drive for pretty much anything over burning a disc as a burned disc puts a lot of stress and strain on the laser when reading from them, thus your laser will die much quicker.