I'm using 4.6A firmware and manager, and I can't get it working in a mode other than Safe Mode (in fact, it didn't even boot in safe mode the first time I flashed it). Safe mode/Trim works fine for me, even on Wifi.
Er, that's for 42 All-Time Classics though. I presume if Clubhouse Games - a later released ROM - works in DoFat, then the G6 team are neglecting (E) ROMs :-/