Besides vitamins and protein powder, I haven't really tried much else. As a med student, everything I've learned tells me that creatine doesn't really work, but there must be something to it if it's one of the best-selling supplements, so I'm willing to give it a try--can't hurt. The worst thing that happens is that I waste money. I know that creatine causes the muscles to retain water, so it's probably more for looks than for increasing functional strength. When someone sees the increase in bulk, it motivates them to workout harder, which is the actual cause for the increase in strength. I have nothing against others using hormones to bulk up, but personally it's not something I would do myself.