I'm currently playing MH3 for the first time and I had no issue's playing this, my current set up is:
FW 3.2E
Wan CIOS ver 10 installed (didn't need to update since then)
game running under USBGX loader with ios 249 and set 002 fix to anti
block ios reload is off
played MH3 for the last 2 hours with no freezing
went online without any problems
working like a charm, I thought I would need this guide to play!!!!!
Great game!!!