Okami.
Fragile Dreams kicks ass, as does Xenoblade. I'm not big on driving games (mariokart is my only exception -barely), hate all smash bros., super preferred Twilight Princess on gamecube, and thought madworld was repetative trash (not that i'm hating on other peoples favs, and i'm sure i'm in an extreme minority as far as wii players go)
Arc Rise Fantasia was awesome as well, though i never finished it.
And the best game i never played - and no one ever will from the looks of it- The Grinder, which IGN still has slated for the now impossible October 2011.