are you using windows or mac?
if you are using windows, right click on the shortcut and see this example:
if your TARGET contains a very long text, or a website, delete the shortcut and create a new one... the target should be simple like on my example..
if your shortcut is a pinned item on the windows start bar, just remove it and create a new one...
several times i had seen people that installed toolbars, after unninstalling the toolbars and clean everything the browser starts at the weird homepage, it took me a lot of time until i figured out the shortcuts were the problem...
this should fix the problem if you already removed everything related to the toolbar\program that created this problem
if you create a new tab and it does still go to this page, someone with safari maybe can tell how to fix that...