I would like it, but at the same time, i wouldn't like it. Why? Because if they do make it, they'll probably use DKR-like graphics compared to MKDS graphics. MKDS > DKR graphics wise on the DS by like 1000%.
Also, since F-Zero is so friggin fast, you should want to easily see what's on the horizon. Kinda hard to do with a low-res screen like that found on the DS.
And on top of that, if Nintendo continues their trend, they're going to kill the game with a bad 2D top view via touchscreen, or they'll add touchscreen perks.
I think that the only way F-Zero would be successful on the DS, is if they could get the 3D view to work on both screens, or if they totally turn off one screen on concentrate on making that view kickass.