Nah, I just checked the MD5 for my SSBM 1.00 iso, it matched the one listed on gametdb and I tested it, the game runs fine on Dolphin.
But yeah, these are the games I've been having trouble running:
SSBM
Eternal Darkness
Prince of Persia: The Two Thrones
Sonic Mega Collection
Sonic Adventure 2 Battle
Warie Ware
Legend of Zelda Four Swords Adventures
Mario Party 4
They either turn the console off after trying to load or freeze it on a black screen.
I've been able to get these games to work:
Mario Kart: Double Dash
Fire Emblem Radiant Dawn
Super Mario Sunshine
Megaman X Collection
Star Fox Adventures
Star Fox Assault
Sonic Heroes
Sonic Adventure DX
Paper Mario TTYD
Soul Caliber II
MGS: The Twin Snakes
Mario Party 5
Luigi's Mansion
Animal Crossing
Prince of Persia: The Sands of Time
F-Zero GX
Battalion Wars
Viewtiful Joe 1, 2, Red Hor Rumble
Wario World
Rogue Squadron 2, 3
Pokemon Colosseum
Pokemon XD
Resident Evil 0,1,2,3,4
Time Splitters 2
Tales of Symphonia